The Fugitive

The Fugitive as a very successful series that aired on ABC from September 1963 to August 1967 with 120 episodes being produced. 

Dr. Richard Kimble is accused, tried, and convicted of the murder of his wife, which he did not commit. While being transported by Lt. Phillip Gerard by train to be executed for the crime, the train derails and Kimble escapes. During the four years the series aired Kimble searched the entire country looking for the one-armed man he saw kill his wife. Kimble assumed different identities and worked odd jobs and was nearly caught numerous times as he continued his relentless search for the killer.